Deeba was introduced as a child actress in film Miss 56 (1956) but Charagh Jalta Raha (1962) was her first film as heroine. Khamosh Raho (1964) was her first big film. Aaina (1966), Sangdil, Behan Bhai (1968), Dard (1969), Sanjna Door Deya, Anjuman (1970), Neend Hamari Khawab Tumharay (1971), Ek Raat (1972), Shama (1974) and Amber (1978) were some of her big films as heroine. She continued as character actress roles and her last film was Zill-e-Shah (2008).
Deeba lost her mother in the partition of the subcontinent in 1947. When Bengali actor Rehman lost his leg in an accident, he decided to produce a film Millan (1964), but he was penny less and no actress was agree to work in this film. At that time Deeba was the only heroine who agreed to work in that film and took only One rupee as signing amount for that film and worked free without any fee. Rehman's program was to shoot this film in East Pakistan (Bangladesh), and Deeba who was in search for her mother, got a golden chance to visit there and look for mother.When the unit of this film reached there, Deeba started searching of her mother, and it is said that she found her there after a long struggle. At the starting of Deeba's film career in early 60s there was a man named Mursaleen, who always had claimed that Deeba was his wife and this case was in the court for many many years. Deeba always denied to this relationship. In the 80's Deeba resided in Dammam, Saudi Arabia for many years where her husband (not Mursaleen) was employed in Saudi Television.