Nasir Khan was the younger brother of the legendary Indian actor Dilip Kumar but he did not gain popularity like him. He began his film career in 1945 from film Mazdoor. He migrated to Pakistan after partition and was selected as hero in first released film Teri Yaad (1948). His second and last film in Pakistan was Shahida (1949). He went back to India and worked in few other Indian movies.
Nasir Khan was married to an actress Begum Para and died on May 3, 1974 at Mumbai.