Mehmood Ali was born in Indian Hyderabad in 1928 and migrated to Pakistan after partition. He joined Radio Pakistan and also worked on Karachi stage. He joined Pakistan Television in 1965 and was remembered for many famous plays.
Mehmood Ali was introduced in Karachi made golden jubilee hit film Banjaran in 1962, but he never got fame in movies. His most popular film was Parday Mein Rehnay Do (1973) and Khush Naseeb in 1984. His last film was Siasat (1986). He was seen in 24 Urdu movies in supporting roles.
Mehmood Ali died on July 11, 2008 in Karachi.